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研究業績Achievements

1. Nakamura Y, Takenaka K, Yamazaki H, Onishi Y, Ozawa Y, Ikegame K, Matsuoka KI, Toubai T, Ueda Y, Kanda Y, Ichinohe T, Atsuta Y, Mori T. Outcome of allogeneic hematopoietic stem cell transplantation in adult patients with paroxysmal nocturnal hemoglobinuria. Int J Hematol. 2021 Jan;113(1):122-127. doi: 10.1007/s12185-020-02982-y. [EPub 2020 Sep 5]
2. Muranushi H, Shindo T, Hishizawa M, Tokunaga M, Wake A, Nakano N, Eto T, Hidaka M, Choi I, Miyamoto T, Uchida N, Moriuchi Y, Miyazaki Y, Fukuda T, Ichinohe T, Atsuta Y, , Kato K; ATL Working Group of the Japanese Society for Hematopoietic Cell Transplantation. GVHD-free, relapse-free survival provides novel clues for optimizing allogeneic-HSCT for adult T-cell leukemia/lymphoma. Bone Marrow Transplant. 2021 Jan;56(1):155-166. doi: 10.1038/s41409-020-00996-y. [EPub 2020 Jul 14]
3. Onishi Y, Mori T, Yamazaki H, Takenaka K, Yamaguchi H, Shingai N, Ozawa Y, Iida H, Ota S, Uchida N, Miyamoto T, Katayama Y, Kato J, Yoshioka S, Onizuka M, Ichinohe T, Atsuta Y; Adult Aplastic Anemia Working Group of the Japan Society for Hematopoietic Cell Transplantation. Cyclosporine/methotrexate versus tacrolimus/methotrexate with or without anti-thymocyte globulin as GVHD prophylaxis in adult patients with aplastic anemia. Ann Hematol. 2021 Jan;100(1):217-228. doi: 10.1007/s00277-020-04290-1. [EPub 2020 Oct 9]
4. Nakano N, Utsunomiya A, Matsuo K, Yoshida N, Seto M, Ohshima K, Fujiwara H, Fuji S, Takatsuka Y, Ito A, Miyamoto T, Suehiro Y, Nakamae H, Sawayama Y, Yuasa M, Miyazaki Y, Ota S, Imada K, Fukuda T, Ichinohe T, Atsuta Y, Kato K. Chromosomal defects and survival in patients with adult T-cell leukemia/lymphoma after allogeneic HSCT. Blood Adv. 2021 Jan:5(2):475-486.
5. Okumoto J, Sakamoto S, Masuda T, Yamaguchi K, Horimasu Y, Miyamoto S, Nakashima T, Iwamoto H,Fukushima N, Fujitaka K, Hamada H, Hattori N. Alectinib-induced immune hemolytic anemia in a patient with lung adenocarcinoma. Intern Med. 2021 Feb 15;60(4):611-615. doi: 10.2169/internalmedicine.4241-19. [Epub 2020 Sep 30]
6. Harada K, Fuji S, Seo S, Uchida N, Kawakita T, Yano S, Ozawa Y, Yoshioka S, Onishi Y, Noguchi Y, Onizuka M, Matsuhashi Y, Kimura T, Ichinohe T, Atsuta Y; Transplant Complications Working Group of the Japan Society for Hematopoietic Cell Transplantation; GVHD Working Group of the Japan Society for Hematopoietic Cell Transplantation, Terakura S, Nakasone H. Comparison of immunosuppressant regimens in salvage cord blood transplantation for graft failure after allogeneic hematopoietic stem cell transplantation. Bone Marrow Transplant. 2021 Feb;56(2):400-410. doi: 10.1038/s41409-020-00999-9. [EPub 2020 Aug 20]
7. Takahashi T, Suzuki R, Yamamoto G, Nakazawa H, Kurosawa M, Kobayashi T, Okada M, Akasaka T, Kim SW, Fukuda T, Ichinohe T, Atsuta Y, Suzumiya J. Hematopoietic stem cell transplantation for diffuse large B-cell lymphoma having 8q24/MYC rearrangement in Japan. Hematol Oncol. 2021 Feb;39(1):66-74. doi: 10.1002/hon.2811. [EPub 2020 Sep 26]
8. Sera Y, Nakata Y, Ueda T, Yamasaki N, Koide S, Kobayashi H, Ikeda KI, Kobatake K, Iwasaki M, Oda H, Wolff L, Kanai A, Nagamachi A, Inaba T, Sotomaru Y, Ichinohe T, Koizumi M, Miyakawa Y, Honda ZI, Iwama A, Suda T, Takubo K, Honda H. UTX maintains functional integrity of murine hematopoietic system by globally regulating aging-associated genes. Blood. 2021 Feb 18;137(7):908-922. doi: 10.1182/blood.2019001044. [EPub 2020 Nov 10]
9. Honjo Y, Takano K, Ichinohe T. Characterization of novel zebrafish MHC class I U lineage genes and their haplotype. Dev Comp Immunol. 2021 Mar;116:103952. doi: 10.1016/j.dci.2020.103952. [EPub 2020 Dec 3]
10. Fujimoto A, Anzai T, Fukuda T, Uchida N, Ohta T, Mori T, Sawa M, Yoshioka S, Miyamoto T, Uchiyama H, Katayama Y, Matsuoka KI, Shiratori S, Nakazawa H, Kanda J, Ichinohe T, Atsuta Y, Fujita N, Kondo E, Suzuki R. Impact of event-free survival status after stem cell transplantation on subsequent survival of patients with lymphoma. Blood Adv. 2021 Mar 9;5(5):1412-1424. doi: 10.1182/bloodadvances.2020003735.
11. Mizuno S, Takami A, Kawamura K, Arai Y, Kondo T, Kawata T, Uchida N, Marumo A, Fukuda T, Tanaka M, Ozawa Y, Yoshida S, Ota S, Takada S, Sawa M, Onizuka M, Kanda Y, Ichinohe T, Atsuta Y, Yanada M. Allogeneic hematopoietic cell transplantation for adolescent and young adult patients with acute myeloid leukemia. Transplant Cell Ther. 2021 Apr;27(4):314.e1-314.e10. doi: 10.1016/j.jtct.2020.12.013. [Epub 2021 Feb 8]
12. Konuma T, Kanda J, Yamasaki S, Harada K, Shimomura Y, Terakura S, Mizuno S, Uchida N, Tanaka M, Doki N, Ozawa Y, Nakamae H, Sawa M, Matsuoka KI, Morishige S, Maruyama Y, Ikegame K, Kimura T, Kanda Y, Ichinohe T, Atsuta Y, Yanada M. Single Cord Blood Transplantation Versus Unmanipulated Haploidentical Transplantation for Adults with Acute Myeloid Leukemia in Complete Remission. Transplant Cell Ther. 2021 Apr;27(4):334.e1-334.e11. doi: 10.1016/j.jtct.2021.01.023. [Epub 2021 Jan 28]
13. Kato M, Dote K, Oda N, Yamane A, Nagai M, Kagawa E, Kunita E, Fukushima N, Ichinohe T. Erdheim-Chester Disease With Left Atrial Pseudotumor Involvement. Circ J. 2021 May 25;85(6):957. doi: 10.1253/circj.CJ-21-0158. [Epub 2021 Apr 13]
14. Iwasa M, Fujii S, Fujishiro A, Maekawa T, Andoh A, Takaori-Kondo A, Ichinohe T, Miura Y. Impact of 2 Gy γ-irradiation on the hallmark characteristics of human bone marrow-derived MSCs. Int J Hematol. 2021 May;113(5):703-711. doi: 10.1007/s12185-020-03072-9. [EPub 2021 Jan 1]
15. Yanada M, Konuma T, Yamasaki S, Kondo T, Fukuda T, Shingai N, Sawa M, Ozawa Y, Tanaka M, Uchida N, Nakamae H, Katayama Y, Matsuoka KI, Kimura T, Kanda Y, Ichinohe T, Atsuta Y, Yano S. Relapse of acute myeloid leukemia after allogeneic hematopoietic cell transplantation: clinical features and outcomes. Bone Marrow Transplant. 2021 May;56(5):1126-1133. doi: 10.1038/ s41409-020-01163-z. [EPub 2020 Dec 2]
16. Isobe M, Konuma T, Masuko M, Uchida N, Miyakoshi S, Sugio Y, Yoshida S, Tanaka M, Matsuhashi Y, Hattori N, Onizuka M, Aotsuka N, Kouzai Y, Wake A, Kimura T, Ichinohe T, Atsuta Y, Yanada M; Adult Acute Myeloid Leukemia Working Group of the Japan Society for Hematopoietic Cell Transplantation. Single cord blood transplantation for acute myeloid leukemia patients aged 60 years or older: a retrospective study in Japan. Ann Hematol. 2021 Jul;100(7):1849-1861. doi: 10.1007/s00277-021-04464-5. [EPub 2021 Feb 23]
17. Terakura S, Kuwatsuka Y, Sugita J, Takahashi S, Ozawa Y, Ozeki K, Yoshioka S, Nakamae H, Kawakita T, Sawa M, Morishige S, Najima Y, Katsuoka Y, Sakaida E, Kouzai Y, Kimura T, Ichinohe T, Fukuda T, Atsuta Y, Murata M, Teshima T. Effect of methotrexate dose in graft-versus-host disease prophylaxis after single-unit cord blood transplantation in adult acute myeloid leukemia. Int J Hematol. 2021 Jun;113(6):840-850. doi: 10.1007/s12185-021-03097-8. [EPub 2021 Feb 21]
18. Yokoyama H, Kanda J, Kawahara Y, Uchida N, Tanaka M, Takahashi S, Onizuka M, Noguchi Y, Ozawa Y, Katsuoka Y, Ota S, Ohta T, Kimura T, Kanda Y, Ichinohe T, Atsuta Y, Nakasone H, Morishima S. Reduced leukemia relapse through cytomegalovirus reactivation in killer cell immunoglobulin-like receptor-ligand-mismatched cord blood transplantation. Bone Marrow Transplant. 2021 Jun;56(6):1352-1363. doi: 10.1038/s41409-020-01203-8. [EPub 2021 Jan 8]
19. Nishii R, Mizuno T, Rehling D, Smith C, Clark BL, Zhao X, Brown SA, Smart B, Moriyama T, Yamada Y, Ichinohe T, Onizuka M, Atsuta Y, Yang L, Yang W, Thomas PG, Stenmark P, Kato M, Yang JJ. NUDT15 polymorphism influences the metabolism and therapeutic effects of acyclovir and ganciclovir. Nat Commun. 2021 Jul 7;12(1):4181. doi: 10.1038/s41467-021-24509-7.
20. Nakamura M, Arai Y, Hirabayashi S, Kondo T, Doki N, Uchida N, Fukuda T, Ozawa Y, Tanaka M, Sawa M, Katayama Y, Kanda Y, Shiratori S, Nakamae H, Yoshioka S, Onizuka M, Ichinohe T, Atsuta Y, Kako S. Residual disease is a strong prognostic marker in patients with acute lymphoblastic leukaemia with chemotherapy-refractory or relapsed disease prior to allogeneic stem cell transplantation. Br J Haematol. 2021 Jul;194(2):403-413. doi: 10.1111/bjh.17646. [Epub 2021 Jun 22]
21. Hirabayashi S, Uozumi R, Kondo T, Arai Y, Kawata T, Uchida N, Marumo A, Ikegame K, Fukuda T, Eto T, Tanaka M, Wake A, Kanda J, Kimura T, Tabuchi K, Ichinohe T, Atsuta Y, Yanada M, Yano S. Personalized prediction of overall survival in patients with AML in non-complete remission undergoing allo-HCT. Cancer Med. 2021 Jul;10(13):4250-4268. doi: 10.1002/cam4.3920. [Epub 2021 Jun 16]
22. Nakamura N, Maruyama D, Machida R, Ichinohe T, Takayama N, Ohba R, Ohmachi K, Imaizumi Y, Tokunaga M, Katsuya H, Yoshida I, Sunami K, Kurosawa M, Kubota N, Morimoto H, Kobayashi M, Kato H, Kameoka Y, Kagami Y, Kizaki M, Takeuchi K, Munakata W, Iida S, Nagai H. Single response assessment of transplant-ineligible multiple myeloma: a supplementary analysis of JCOG1105 (JCOG1105S1). Jpn J Clin Oncol. 2021 Jul 1;51(7):1059-1066. doi: 10.1093/jjco/hyab066.
23. Shimomura Y, Hara M, Yamamoto H, Uchida N, Kawakita T, Ashida T, Takada S, Ikeda T, Morishige S, Maruyama Y, Wake A, Ichinohe T, Fukuda T, Takanashi M, Atsuta Y, Ishikawa T. Adding melphalan to fludarabine and a myeloablative dose of busulfan improved survival after allogeneic hematopoietic stem cell transplantation in a propensity score-matched cohort of hematological malignancies. Bone Marrow Transplant. 2021 Jul;56(7):1691-1699. doi: 10.1038/s41409-021-01217-w. [EPub 2021 Mar 3]
24. Yanada M, Uchida N, Ichinohe T, Fukuda T, Kanda J, Kanda Y, Atsuta Y, Nakasone H. Does one model fit all? Predicting non-relapse mortality after allogeneic hematopoietic cell transplantation. Bone Marrow Transplant. 2021 Jul;56(7):1720-1722. doi: 10.1038/s41409-021-01236-7. [EPub 2021 Mar 3]
25. Kurosawa S, Mizuno S, Arai Y, Masuko M, Kanda J, Kohno K, Onai D, Fukuda T, Ozawa Y, Katayama Y, Tanaka M, Ikegame K, Uchida N, Eto T, Ota S, Tanaka J, Ichinohe T, Atsuta Y, Yanada M. Syngeneic hematopoietic stem cell transplantation for acute myeloid leukemia: a propensity score-matched analysis. Blood Cancer J. 2021 Sep 24;11(9):159. doi: 10.1038/s41408-021-00553-w.
26. Shimomura Y, Hara M, Hirabayashi S, Kondo T, Mizuno S, Uchida N, Mukae J, Kawakita T, Fukuda T, Kanda Y, Ota S, Ozawa Y, Eto T, Maruyama Y, Tanaka M, Nakano N, Kimura T, Ichinohe T, Atsuta Y, Yanada M. Comparison of fludarabine, a myeloablative dose of busulfan, and melphalan vs conventional myeloablative conditioning regimen in patients with relapse and refractory acute myeloid leukemia in non-remission status. Bone Marrow Transplant. 2021 Sep;56(9):2302-2304. doi: 10.1038/s41409-021-01380-0. [Epub 2021 Jun 21]
27. Shiratori S, Sugita J, Fuji S, Aoki J, Sawa M, Ozawa Y, Hashimoto D, Matsuoka KI, Imada K, Doki N, Ashida T, Ueda Y, Tanaka M, Sawayama Y, Ichinohe T, Terakura S, Morishima S, Atsuta Y, Fukuda T, Teshima T. Low-dose antithymocyte globulin inhibits chronic graft-versus-host disease in peripheral blood stem cell transplantation from unrelated donors. Bone Marrow Transplant. 2021 Sep;56(9):2231-2240. doi: 10.1038/s41409-021-01314-w. [Epub 2021 May 7]
28. Takada Y, Shibuta T, Hatano M, Sato K, Koga M, Ishibashi A, Harada T, Hisatomi T, Shimura H, Fukushima N, Leecharoenkiat K, Chamnanchanunt S, Svasti S, Fucharoen S, Umemura T. Pre-analytical modification of serum miRNAs: diagnostic reliability of serum miRNAs in hemolytic diseases. J Clin Med. 2021 Oct 28;10(21):5045. doi: 10.3390/jcm10215045.
29. Seo S, Usui Y, Matsuo K, Atsuta Y, Igarashi A, Fukuda T, Ozawa Y, Katayama Y, Yoshida S, Uchida N, Kondo T, Kako S, Tsukada N, Kato S, Onizuka M, Ichinohe T, Kimura F, Kanda Y, Miyamura K, Kanda J; JSHCT Donor Source Working Group. Impact of the combination of donor age and HLA disparity on the outcomes of unrelated bone marrow transplantation. Bone Marrow Transplant. 2021 Oct;56(10):2410-2422. doi: 10.1038/s41409-021-01289-8. [Epub 2021 May 14]
30. Murata M, Terakura S, Wake A, Miyao K, Ikegame K, Uchida N, Kataoka K, Miyamoto T, Onizuka M, Eto T, Doki N, Ota S, Sato M, Hashii Y, Ichinohe T, Fukuda T, Atsuta Y, Okamoto S, Teshima T. Off-the-shelf bone marrow-derived mesenchymal stem cell treatment for acute graft-versus-host disease: real-world evidence.Bone Marrow Transplant. 2021 Oct;56(10): 2355-2366. doi: 10.1038/s41409-021-01304-y. [Epub 2021 May 11]
31. Inoue T, Koyama M, Kaida K, Ikegame K, Ensbey KS, Samson L, Takahashi S, Zhang P, Minnie SA, Maruyama S, Ishii S, Daimon T, Fukuda T, Nakamae H, Ara T, Maruyama Y, Ishiyama K, Ichinohe T, Atsuta Y, Blazar BR, Furlan SN, Ogawa H, Hill GR. Peritransplant glucocorticoids redistribute donor T cells to the bone marrow and prevent relapse after haploidentical SCT. JCI Insight. 2021 Nov 22;6(22):e153551. doi: 10.1172/jci.insight. 153551.
32. Kako S, Hayakawa F, Imai K, Tanaka J, Mizuta S, Nishiwaki S, Kanamori H, Mukae J, Ozawa Y, Kondo T, Fukuda T, Ichinohe T, Ota S, Tanaka Y, Murayama T, Kurahashi S, Sakura T, Usui N, Ohtake S, Kiyoi H, Matsumura I, Miyazaki Y, Atsuta Y. Optimal treatment for Philadelphia-negative acute lymphoblastic leukemia in first remission in the era of high-intensity chemotherapy. Int J Hematol. 2021 Nov;114(5):608-619. doi: 10.1007/s12185-021-03198-4. [Epub 2021 Jul 30]
33. Konuma T, Kondo T, Masuko M, Shimizu H, Shiratori S, Fukuda T, Kato J, Sawa M, Ozawa Y, Ota S, Uchida N, Kanda Y, Kako S, Fujisawa S, Fukushima K, Ichinohe T, Atsuta Y, Yanada M; Adult Acute Myeloid Leukemia Working Group of the Japan Society for Hematopoietic Cell Transplantation. Prognostic value of measurable residual disease at allogeneic transplantation for adults with core binding factor acute myeloid leukemia in complete remission. Bone Marrow Transplant. 2021 Nov;56(11):2779-2787. doi: 10.1038/s41409-021-01409-4. [Epub 2021 Jul 16]
34. Edahiro T, Kawase T, Nagoshi H, Fujino K, Toishigawa K, Miyama T, Mino T, Yoshida T, Morioka T, Hirata Y, Noma M, Fujii T, Nishizawa M, Fukushima N, Ichinohe T. Allogeneic hematopoietic cell transplantation using fludarabine plus myeloablative busulfan and melphalan confers promising survival in high-risk hematopoietic neoplasms: a single-center retrospective analysis. Hematology. 2021 Dec;26(1):186-198. doi: 10.1080/16078454. 2021.1881228. [EPub 2021 Feb 17]
35. Chishaki R, Fukushima N, Ishikawa C, Edahiro T, Mino T, Yoshida T, Nishizawa M, Ichinohe T. Sudden hearing loss in a young patient with chronic myelogenous leukemia. Hiroshima J Med Sci. 2021 Dec;70: 39-42.
36. Shimazu Y, Mizuno S, Fuchida SI, Suzuki K, Tsukada N, Hanagaishi A, Itagaki M, Kataoka K, Kako S, Sakaida E, Yoshioka S, Iida S, Doki N, Oyake T, Ichinohe T, Kanda Y, Astuta Y, Takamatsu H; working group of the Japan Society for Transplantation, Cellular Therapy. Improved survival of multiple myeloma patients treated with autologous transplantation in the modern era of new medicine. Cancer Sci. 2021 Dec;112(12):5034-5045. doi: 10.1111/cas.15163. [Epub 2021 Oct 26]
37. Shiratori S, Kurata M, Sugita J, Ota S, Kasahara S, Ishikawa J, Imada K, Onishi Y, Ishiyama K, Ashida T, Kanda Y, Ichinohe T, Fukuda T, Atsuta Y, Teshima T. Graft-Versus-Host Disease Prophylaxis Using Low-Dose Antithymocyte globulin in peripheral blood stem cell transplantation-a matched-pair analysis. Transplant Cell Ther. 2021 Dec;27(12):995.e1-995.e6. doi: 10.1016/j.jtct.2021.08.029. [Epub 2021 Sep 6]
38. Yanada M, Konuma T, Yamasaki S, Harada K, Iwasaki M, Kobayashi A, Nishijima A, Tanaka M, Uchida N, Nakamae H, Fukuda T, Onizuka M, Ozawa Y, Sawa M, Katayama Y, Yoshioka S, Kimura T, Ichinohe T, Atsuta Y, Kanda J, Yano S. Allogeneic hematopoietic cell transplantation from alternative donors in acute myelogenous leukemia: a comparative analysis. Transplant Cell Ther. 2021 Dec;27(12):1005.e1-1005.e8. doi: 10.1016/j.jtct. 2021.08.027. [Epub 2021 Sep 6]
39. Fuji S, Hakoda A, Kanda J, Murata M, Terakura S, Inamoto Y, Uchida N, Toya T, Eto T, Nakamae H, Ikegame K, Tanaka M, Kawakita T, Kondo T, Miyamoto T, Fukuda T, Ichinohe T, Kimura T, Atsuta Y, Shintani A, Morishima S. Impact of HLA disparity on the risk of overall mortality in patients with grade II-IV acute GVHD on behalf of the HLA Working Group of Japan Society for Hematopoietic Cell Transplantation. Bone Marrow Transplant. 2021 Dec;56(12):2990-2996. doi: 10.1038/s41409-021-01443-2. [Epub 2021 Sep 3]
40. Yanada M, Mizuno S, Yamasaki S, Harada K, Konuma T, Tamaki H, Shingai N, Uchida N, Ozawa Y, Tanaka M, Onizuka M, Sawa M, Nakamae H, Shiratori S, Matsuoka KI, Eto T, Kawakita T, Maruyama Y, Ichinohe T, Kanda Y, Atsuta Y, Aoki J, Yano S. Difference in outcomes following allogeneic hematopoietic cell transplantation for patients with acute myeloid leukemia and myelodysplastic syndromes. Leuk Lymphoma. 2021 Dec;62(14):3411-3419. doi: 10.1080/10428194.2021.1961242. [Epub 2021 Aug 4]
41. Kuroda Y, Koyama D, Kikuchi J, Mori S, Ichinohe T, Furukawa Y. Autophagic degradation of NOXA underlies stromal cell-mediated resistance to proteasome inhibitors in mantle cell lymphoma. Leuk Res. 2021 Dec;111:106672. doi: 10.1016/j.leukres.2021.106672. [Epub 2021 Jul 24]