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研究業績Achievements

1. Kanda J, Hayashi H, Ruggeri A, Kimura F, Volt F, Takahashi S, Labopin M, Kako S, Tozatto-Maio K, Yano-S, Sanz G, Uchida N, Van Lint MT, Kato S, Mohty M, Forcade E, Kanamori H, Sierra J, Ohno Y, Saccardi R, Fukuda T, Ichinohe T, Takanashi M, Rocha V, Ikamoto S, Nagler A, Atsuta Y, Gluckman E. Prognostic factors for adult single cord blood transplantation among European and Japanese populations: the Eurocord/ALWP-EBMT and JSHCT./JDHCT collaborative study. Leukemia. 2020 Jan; 34(1):128-137. doi: 10.1038 /s41375-019-0534-5 [EPub 2019 Aug 14]
2. Yamasaki S, Aoki J, Mori J, Mizuno S, Uchida N, Ohashi K, Fukuda T, Ikegame K, Eto T, Ogawa Y, Tanaka M, Hidaka M, Iwato K, Sawa M, Ichinohe T, Kanda Y, Atsuta Y, Yanada M, Yano S; Adult Acute Myeloid Leukemia Working Group of the Japan Society for Hematopoietic Cell Transplantation. Better disease control before allogeneic stem cell ransplantation is crucial to improve the outcomes of transplantation for acute myeloid leukemia with extramedullary disease. Bone Marrow Transplant. 2020 Jan;55(1):249-252. doi: 10.1038/s41409-019-0527-z [EPub 2019 Apr 10]
3. Morishima Y, Morishima S, Muurata M, Arima N, Uchida N, Sugio Y, Takahashi S, Matsuhashi Y, Onizuka M, Eto T, Nagafuji K, Onishi Y, Inoue M, Atsuta Y, Fukuda T, Ichinohe T, Kato S, Kanda J. Impact of homozygous conserved extended HLA haplotype on single cord blood transplantation: lessons for induced pluripotent stem cell banking and transplantation in allogeneic settings. Biol Blood Marrow Transplant. 2020 Jan;26(1):132-138. doi: 10.1016/j.bbmt.2019.09.009. [EPub 2019 Sep 12]
4. Yanada M, Takami A, Mizuno S, Mori J, Chou T, Usuki K, Uchiyama H, Amano I, Fuji S, Miyamoto T, Saito T, Kamimura T, Ichinohe T, Fukuda T, Okamoto S, Atsuta Y, Yano S. Autologous hematopoietic cell transplantation for acute myeloid leukemia in adults: 25 years of experience in Japan. Int J Hematol. 2020 Jan;111(1):93-102. doi: 10.1007/s12185-019-02759-y. [EPub 2019 Oct 14]
5. Nagoshi H, Toishigawa K, Inoue T, Okikawa Y, Miyama T, Kawase T, Edahiro T, Kazihara K, Nakagawa H, Yamaoka A, Noma M, Fujii T, Fukushima N, Ichinohe T. CD56-positive B-cell precursor acute lymphoblastic leukemia harboring KMT2A-AFF1 rearrangement developed in a pregnant woman successfully treated with allogeneic hematopoietic cell transplantation. J Hematopathol. 2020 Jan 7;13(4):47-49. doi: 10.1007/s12308-019-00383-7
6. Matsumoto Y, Chinen Y, Shimura Y, Nagoshi H, Sasaki N, Muramatsu A, Kuriyama K, Ohshiro M, Hirakawa Y, Iwai T, Uchiyama H, Taki T, Horiike S, Kuroda J, Taniwaki M. Recurrent intragenic exon rearrangements of SOBP and AUTS2 in non-Hodgkin B-cell lymphoma. Int J Hematol. 2020 Jan;111(1):75-83. doi: 10.1007/s12185-019-02766-z. [Epub 2019 Nov 4]
7. Takasu M, Kondo S, Akiyama Y, Takahashi Y, Maeda S, Baba Y, Kawase T, Ichinohe T, Awai K. Assessment of early treatment response on MRI in multiple myeloma: Comparative study of whole-body diffusion-weighted and lumbar spinal MRI. PLoS One. 2020 Feb 27;15(2):e0229607. doi: 10.1371/journal.pone.0229607. eCollection 2020.
8. Kako S, Yamazaki H, Ohashi K, Ozawa Y, Ota S, Kanda Y, Maeda T, Kato J, Ishiyama K, Matsuoka KI, Miyamoto T, Iida H, Ikegame K, Fukuda T, Ichinohe T, Atsuta Y, Mori T; Adult Aplastic Anemia Working Group of the Japan Society for Hematopoietic Cell Transplantation. Mixed chimerism and secondary graft Failure in allogeneic hematopoietic stem cell transplantation for aplastic anemia. Biol Blood Marrow Transplant. 2020 Mar;26(3):445-450. pii: S1083-8791(19)30655-X. doi: 10.1016/j.bbmt.2019.09.035. [EPub 2019 Oct 13]
9. Konuma T, Kondo T, Mizuno S, Doki N, Aoki J, Fukuda T, Tanaka M, Sawa M, Katayama Y, Uchida N, Ozawa Y, Morishige S, Matsuoka KI, Ichinohe T, Onizuka M, Kanda J, Atsuta Y, Yanada M; Adult Acute Myeloid Leukemia Working Group of the Japan Society for Hematopoietic Cell Transplantation. Conditioning intensity for allogeneic hematopoietic stem cell transplantation in acute myeloid leukemia patients with poor-prognosis cytogenetics in first complete remission. Biol Blood Marrow Transplant. 2020 Mar;26(3):463-471. doi: 10.1016/j.bbmt.2019.09.025. [EPub 2019 Sep 25]
10. Kanda J, Kawase T, Tanaka H, Kojima H, Morishima Y, Uchida N, Nagafuji K, Matsuhashi Y, Ohta T, Onizuka M, Sakura T, Takahashi S, Miyakoshi S, Kobayashi H, Eto T, Tanaka J, Ichinohe T, Atsuta Y, Morishima S; HLA Working Group of the Japan Society for Hematopoietic Cell Transplantation. Effects of haplotype matching on outcomes after adult single-cord blood transplantation. Biol Blood Marrow Transplant. 2020 Mar;26(3):509-518. doi: 10.1016/j.bbmt.2019.09.035. [EPub 2019 Oct 9]
11. Arima N, Kanda J, Yabe T, Morishima Y, Tanaka J, Kako S, Sakaguchi H, Kako M, Ohashi K, Ozawa Y, Fukuda T, Ota S, Tachibana T, Onizuka M, Ichinohe T, Atsuta Y, Kanda Y. Increased relapse risk of acute lymphoid leukemia in homozygous HLA-C1 patients after HLA-matched allogeneic transplantation: a Japanese national registry study. Biol Blood Marrow Transplant. 2020 Mar;26(3):431-437. doi: 10.1016/j.bbmt.2019.10.032. [EPub 2019 Nov 6]
12. Yokoyama H, Morishima Y, Fuji S, Uchida N, takahashi S, Onizuka M, Tanaka M, Yuji O, Eto T, Ozawa Y, Takada S, Takanashi M, Kato K, Kanda Y, Ichinohe T, Atsuta Y, Kanda J; HLA Working Group of the Japan Society for Hematopoietic Cell Transplantation. Impact of HLA allele match at HLA-A, -B, -C, and -DRB1 in single cord blood transplantation. Biol Blood Marrow Transplant. 2020 Mar;26(3):519-528. doi: 10.1016/j.bbmt.2019.11.001. [EPub 2019 Nov 9]
13. Yoshimitsu M, Fuji S, Utsunomiya A, Nakano N, Ito A, Ito Y, Miyamoto T, Suehiro Y, Kawakita T, Moriuchi Y, Nakamae H, Kanda Y, Ichinohe T, Fukuda T, Atsuta Y, Kako K. Outcomes of allogeneic hematopoietic stem cell transplantation for ATL with HTLV-1 antibody positive donors: allo-HCT for ATL from HTLV-1 antibody positive donors. Biol Blood Marrow Transplant. 2020 Apr;26(4):718-722. pii: S1083-8791(19)30839-0. doi: 10.1016/ j.bbmt.2019.12.004. [EPub 2019 Dec 7]
14. Fujimoto A, Hiramoto N, Yamasaki S, Inamoto Y, Ogata M, Sugio Y, Fukuda T, Uchida N, Ikegame K, Matsuoka KI, Shiratori S, Kondo T, Eto T, Ichinohe T, Kanda Y, Atsuta Y, Suzuki R; Complication Working Group of the Japan Society for Hematopoietic Cell Transplantation. Low incidence of posttransplant lymphoproliferative disorder after allogeneic stem cell transplantation in patients with lymphoma treated with rituximab. Hematol Oncol. 2020 Apr;38(2):146-152. doi: 10.1002/hon.2714. [EPub 2020 Jan 17]
15. Fuji S, Oshima K, Ohashi K, Sawa M, Saito T, Eto T, Tanaka M, Onizuka M, Nakamae H, Shiratori S, Ozawa Y, Hidaka M, Nagamura-Inoue T, Tanaka H, Fukuda H, Ichinohe T, Atsuta Y, Ogata M. Impact of pretransplant donor-specific anti-HLA antibodies on cord blood transplantation on behalf of the Transplant Complications Working Group of the Japan Society for Hematopoietic Cell Transplantation. Bone Marrow Transplant 2020 Apr;55(4):722-728. doi: 10.1038/s41409-019-0712-0. [EPub 2019 Oct 7]
16. Kobatake K, Ikeda K-I, Nakata Y, Yamasaki N, Ueda T, Kanai A, Sentani K, Sera Y, Hayashi T, Koizumi M, Miyakawa Y, Inaba T, Sotomaru Y, Kaminuma O, Ichinohe T, Honda Z, Yasui W, Horie S, C. Black P, Matsubara A, Honda H. Kdm6a deficiency activates inflammatory pathways, promotes M2 macrophage polarization, and causes bladder cancer in cooperation with p53 dysfunction. Clin Cancer Res. 2020 Apr 15;26(8):2065-2079. doi: 10.1158/1078-0432.CCR-19-2230. [EPub 2020 Feb 11]
17. Yabe H, Tabuchi K, Uchida N, Takahashi S, Onishi Y, Aotsuka N, Sugio Y, Ikegame K, Ichinohe T, Takahashi M, Kato K, Atsuta Y, Kanda Y. Could the minimum number of haematopoietic stem cells to obtain engraftment exist in unrelated, single cord blood transplantation? Br J Haematol. 2020 Apr;189(2):e56-e60. doi: 10.1111/bjh.16465. [Epub 2020 Feb 28]
18. Togashi T, Meguro-Horike M, Nagaya S, Sugihara S, Ichinohe T, Araiso Y, Yamaguchi K, Mori K, Imai Y, Kuzasa K, Horike S, Asakura H, Watanabe A, Morishita E. Molecular genetic analysis of inherited protein C deficiency caused by the novel large deletion across two exons of PROC. Thrombosis Research. Thromb Res. 2020 Apr;188:115-118. doi: 10.1016/j.thromres.2020.03.009. [Epub 2020 Mar 10]
19. Kawamura K, Kanda J, Ohashi K, Fukuda T, Iwato K, Eto T, Fujiwara SI, Mori T, Fukushima K, Ozawa Y, Uchida N, Ashida T, Ichinohe T, Atsuta Y, Kanda Y. Influence of HLA 1-3-locus mismatch and antithymocyte globulin administration in unrelated bone marrow transplantation. Ann Hematol. 2020 May;99(5):1099-1110. doi: 10.1007/s00277-020-03995-7. [Epub 2020 Mar 23]
20. Kato M, Nakasone H, Nakano N, Fuji S, Shinohara A, Yokoyama H, Sakashita K, Hori T, Takahashi S, Nara M, Kanda Y, Mori T, Takita J, Kawaguchi H, Kawakita T, Ichinohe T, Fukuda T, Atsuta Y, Ogata M; Transplant Complications Working Group of the Japan Society for Hematopoietic Cell Transplantation. Clinical course of autologous recovery with chromosomal abnormalities after allogeneic hematopoietic stem cell transplantation. Bone Marrow Transplant 2020 Jun;55(6):1023-1028. doi: 10.1038/s41409-019-0765-0. [EPub 2019 Dec 9]
21. Ureshino H, Koarada S, Kamachi K, Yoshimura M, Yoo M, Kunota Y, Ando T, Ichinohe T, Morio T, Kumura S. Imuune dydregulation syndrome with de novo CTLA4 germline mutation responsive to abatacept therapy. Int J Hematol. 2020 Jun;111(6):897-902. doi: 10.1007/s12185-020-02834-9. [EPub 2002 Jan 28]
22. Honjo Y, Ichinohe T. °Stage-specific effects of ionizing radiation during early development. Int J Mol Sci. 2020 Jun 1;21(11):3975. doi: 10.3390/ijms21113975.
23. Yanada M, Takami A, Yamasaki S, Arai Y, Konuma T, Uchida N, Najima Y, Fukuda T, Tanaka M, Ozawa Y, Ikegame K, Takanashi M, Ichinohe T, Okamoto S, Atsuta Y, Yano S. Allogeneic hematopoietic cell transplantation for adults with acute myeloid leukemia conducted in Japan during the past quarter century. Ann Hematol. 2020 Jun;99(6):1351-1360. doi: 10.1007/s00277-020-04051-0. [Epub 2020 May 4]
24. Ueno H, Kikumto M, Takebayashi Y, Ishibashi H, Takahashi T, Yasutomi H, Umemoto K, Nakamichi K, Saijo M, Ichinohe T, Maruyama H. Pomalidomide-associated progressive multifocal leukoencephalopathy in multiple myeloma: cortical susceptibility-weighted imaging hypointense findings prior to clinical deterioration. J Neurovirol. 2020 Jun;26(3):452-455. doi: 10.1007/s13365-020-00845-0. [Epub 2020 May 11]
25. Kaito S, Najima Y, Harada K, Fukuda T, Noguchi Y, Ikegame K, Tanaka M, Ozawa Y, Yoshida S, Sawa M, Ota S, Inoue Y, Tanaka J, Ichinohe T, Atsuta Y, Kako S; on behalf of Adule Lymphoblastic Leukemia Working Group of the Japan Society for Hematopoietic Cell Transplantation. Allogeneic hematopoietic stem cell transplantation for adult patients with B-cell acute lymphoblastic leukemia harboring t(1;19)(q23;p13.3); comparison with normal karyotype. Bone Marrow Transplant 2020 Jul;55(7):1337-1346. doi: 10.1038/s41409-020-0816-6. [Epub 2020 Feb 10]
26. Akahoshi Y, Igarashi A, Fukuda T, Uchida N, Tanaka M, Ozawa Y, Kanda Y, Onizuka M, Ichinohe T, Tanaka J, Atsuta Y, Kako S; Adult Acute Lymphoblastic Leukemia Working Group of the Japan Society for Hematopoietic Cell Transplantation. Impact of graft-versus-host disease and graft-versus-leukemia effect based on minimal residual disease in Philadelphia chromosome-positive acute lymphoblastic leukemia. Br J Haematol. 2020 Jul;190(1):84-92. doi: 10.1111/bjh.16540. [Epub 2020 Mar 2]
27. Sakurai M, Mori T, Uchiyama H, Ago H, Iwato K, Eto T, Iwasaki H, Kawata T, Takamatsu H, Yamasaki S, Takanashi M, Ichinohe T, Atsuta Y, Suzuki R. Outcome of stem cell transplantation for Waldenström's macroglobulinemia: analysis of the Japan Society for Hematopoietic Cell Transplantation (JSHCT) Lymphoma Working Group. Ann Hematol. 2020 Jul;99(7):1635-1642. doi: 10.1007/s00277-020-04078-3. [Epub 2020 May 18]
28. Edahiro T, Morioka T, Toishigawa K, Nagoshi H, Kawase T, Fukushima N, Ichinohe T. Streptococcus gallolyticus ssp. pasteurianus bacteremia during chemotherapy induced neutropenia in a patient with malignant lymphoma. Hiroshima Journal of Medical Science. 2020;69(2):47-50.
29. Kida M, Usuki K, Uchida N, Fukuda T, Katayama Y, Kondo T, Eto T, Matsuoka KI, Matsuhashi Y, Ota S, Sawa M, Miyamoto T, Ichinohe T, Kimura T, Atsuta Y, Takami A, Miyazaki Y, Yano S, Ishiyama K, Yanada M, Aoki J. Outcome and Risk Factors for Therapy-Related Myeloid Neoplasms Treated with Allogeneic Stem Cell Transplantation in Japan. Biol Blood Marrow Transplant. 2020 Aug;26(8):1543-1551. doi: 10.1016/ j.bbmt.2020.04.004. [Epub 2020 Apr 19]
30. Kusumoto S, Tanaka Y, Suzuki R, Watanabe T, Nakata M, Sakai R, Fukushima N, Fukushima T, Moriuchi Y, Itoh K, Nosaka K, Choi I, Sawa M, Okamoto R, Tsujimura H, Uchida T, Suzuki S, Okamoto M, Takahashi T, Sugiura I, Onishi Y, Kohri M,Yoshida S, Kojima M, Takahashi H, Tomita A, Atsuta Y, Maruyama D, Tanaka E, Suzuki T, Kinoshita T, Ogura M, Ueda R, Mizokami M. Ultra-high sensitivity HBsAg assay can diagnose HBV reactivation following rituximab-based therapy in patients with lymphoma. J Hepatol. 2020 Aug;73(2):285-293. doi: 10.1016/j.jhep.2020.03.009. [Epub 2020 Mar 17]
31. Murata M, Suzuki R, Nishida T, Shirane S, Shimazu Y, Minami Y, Mori T, Doki N, Kanda Y, Uchida N, Tanaka M, Ishikawa J, Togitani K, Fukuda T, Ichinohe T, Atsuta Y, Nagamura-Inoue T, Kiyoi H. Allogeneic Hematopoietic Stem Cell Transplantation for Post-essential Thrombocythemia and Post-polycythemia Vera Myelofibrosis. Intern Med. 2020;59(16):1947-1956. doi: 10.2169/internalmedicine.4375-19. [Epub 2020 Aug 15]
32. Yokoyama Y, Maie K, Fukuda T, Uchida N, Mukae J, Sawa M, Kubo K, Kurokawa M, Nakamae H, Ichinohe T, Atsuta Y, Chiba S. A high CD34+ cell dose is associated with better disease-free survival in patients with with low-risk diseases undergoing peripheral blood stem cell transplantation from HLA-matched related donors. Bone Marrow Transplant. 2020 Sep;55(9):1726-1735. °doi: 10.1038/s41409-020-0817-5. [Epub 2020 Feb 10]*
33. Kurosawa S, Shimomura Y, Tachibana T, Ishiyama K, Ota S, Kobayashi T, Uchida N, Fukushima K, Ashida T, Matsuoka KI, Kanda J, Ichinohe T, Atsuta Y, Murata M, Aoki J. Outcome of allogeneic hematopoietic stem cell transplantation in patients with myelodysplastic/myeloproliferative neoplasms-unclassifiable: a retrospective nationwide study of the Japan Society for Hematopoietic Cell Transplantation. Biol Blood Marrow Transplant. 2020 Sep;26(9):1607-1611. °doi: 10.1016/j.bbmt.2020.05.013. [EPub 2020 May 23]
34. Tachibana T, Najima Y, Akahoshi Y, Hirabayashi S, Harada K, Doki N, Uchida N, Fukuda T, Sawa M, Ogata M, Takada S, Tanaka M, Matsuhashi Y, Tanaka J, Onizuka M, Ichinohe T, Atsuta Y, Kako S; Adult ALL Working Group of the Japan Society for Hematopoietic Cell Transplantation. The impacts of BCR-ABL1 mutations in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia who underwent allogeneic hematopoietic cell transplantation. Ann Hematol. 2020 Oct;99(10):2393-2404. doi: 10.1007/s00277-020-04212-1. [Epub 2020 Aug 15]
35. Yanada M, Fukuda T, Tanaka M, Ota S, Toya T, Mori T, Uchida N, Ozawa Y, Nakamae H, Kanda Y, Ichinohe T, Atsuta Y, Yano S. Long-term results of reduced-intensity conditioning allogeneic hematopoietic cell transplantation for older patients with acute myeloid leukemia: a retrospective analysis of 10-year follow-up data. Bone Marrow Transplant. 2020 Oct;55(10):2008-2016. °doi: 10.1038/s41409-020-0868-7. [Epub 2020 Mar 20] *
36. Miyao K, Terakura S, Kimura F, Konuma T, Miyamura K, Yanada M, Kako S, Morhishima S, Uchida N, Toya T, Ozawa Y, Fukuda T, Tanaka M, Sawa M, Takada S, Yoshida S, Kimura T, Ichinohe T, Atsuta Y, Kanda J; Donor/Source Working Group of the Japan Society for Hematopoietic Cell Transplantation. Updated Comparison of 7/8 HLA Allele-Matched Unrelated Bone Marrow Transplantation and Single-Unit Umbilical Cord Blood Transplantation as Alternative Donors in Adults with Acute Leukemia. Biol Blood Marrow Transplant. 2020 Nov;26(11):2105-2114. °doi: 10.1016/j.bbmt.2020.08.001. [EPub 2020 Aug 9]
37. Kuwatsuka Y, Atsuta Y, Hirakawa A, Uchida N, Inamoto Y, Najima Y, Ikegame K, Eto T, Ozawa Y, Ichinohe T, Inoue M, Kimura T, Okamoto S, Miyamura K, Fukuda T. Use of unapproved or off-label drugs in Japan for the treatment of graft-versus-host disease and post-transplant viral infection. Int J Hematol. 2020 Dec;112(6):841-850. doi: 10.1007/s12185-020-02972-0. [2020 Sep 1.]
38. Konuma T, Ishiyama K, Doki N, Uchida N, Ozawa Y, Fukuda T, Ueda Y, Matsuoka KI, Mori T, Katayama Y, Onizuka M, Ichinohe T, Atsuta T; Adult Myelodysplastic Syndrome Working Group of the Japan Society for Hematopoietic Cell Transplantation. Are there graft-versus-myelodysplastic syndrome effects after allogeneic hematopoietic cell transplantation?: A retrospective study from the Japan Society for Hematopoietic Cell Transplantation. Clin Cancer Res. 2020 Dec 15;26(24):6483-6493. doi: 10.1158/ 1078-0432.CCR-20-1104. [Epub 2020 Sep 6]